離散數值因子僅使用兩個水平，因此可以定義為連續或分類因子。 這項變更將使最終的篩選設計成為候選。
DOE(
Definitive Screening Design,
{Add Response( Maximize, "Y", ., ., . ), Add Factor( Blocking, 0, "Block" ),
Add Factor( Continuous, 0, 100, "Imidazol conc.", 0 ),
Add Factor( Categorical, {"Yes", "No"}, "Perform dialysis in cartridge", 0 ),
Add Factor( Categorical, {"Homemade", "Readymixed"}, "Dialysis buffer", 0 ),
Add Factor( Continuous, 0, 100, "Covered surface in fridge", 0 ),
Add Factor( Continuous, 0, 100, "Centrifugation", 0 ),
Add Factor( Categorical, {"0", "2"}, "Concentration cycles", 0 ),
Show Blocking Options( 1, 4 ), Number of Extra Runs( 4 ),
Set Random Seed( 2118942861 ), Make Design, Simulate Responses( 0 ),
Save X Matrix( 0 )}
);你好@本根根巴赫,
我嘗試使用您指定的別名產生篩選設計。
如果我們用 X1、X2、... 對您的因子（區塊除外）進行“編碼”，則表示您擁有用於部分因子設計的產生器：I = 1245。
然而，該區塊的存在很難考慮，因為我們必須注意它不與主效應或任何其他效應混淆，這是一項非常棘手的任務，因為別名在這裡是固定的。
當嘗試在生成規則中設定此生成器時，這是我的配置：
因此，這是一個使用您定義的別名的設計範例（附表）：
DOE(
Screening Design,
{Add Response( Maximize, "Y", ., ., . ), Add Factor,
Add Factor( Continuous, 0, 100, "Imidazol conc.", 0 ),
Add Factor( Categorical, {"Yes", "No"}, "Perform dialysis in cartridge", 0 ),
Add Factor( Categorical, {"Homemade", "Readymixed"}, "Dialysis buffer", 0 ),
Add Factor( Continuous, 0, 100, "Covered surface in fridge", 0 ),
Add Factor( Continuous, 0, 100, "Centrifugation", 0 ),
Add Factor( Discrete Numeric, {0, 2}, "Concentration cycles", 0 ),
Set Random Seed( 1921021643 ), Make Design( 6 ),
Set Generators( [1 1 0 1, 1 1 0 1, 0 1 1 0, 1 0 1 0, 1 1 2 2, 0 0 0 0] ),
Simulate Responses( 0 ), Save X Matrix( 0 )}
)
但正如建議的@馬克貝利，我還推薦自訂設計，因為您有不同類型的因子（DSD 接受 2 級分類和連續因子，但不接受離散數字因子），如果您對每天的運行次數或任何其他阻塞變數有任何限制，並且您可以避免在設計中出現完全混疊的效果。
根據您的因素進行可能的客製化篩選設計的範例可能是：
DOE(
Custom Design,
{Add Response( Maximize, "Y", ., ., . ),
Add Factor( Continuous, 0, 100, "Imidazol conc.", 0 ),
Add Factor( Categorical, {"Yes", "No"}, "Perform dialysis in cartridge", 0 ),
Add Factor( Categorical, {"Homemade", "Readymixed"}, "Dialysis buffer", 0 ),
Add Factor( Continuous, 0, 100, "Covered surface in fridge", 0 ),
Add Factor( Continuous, 0, 100, "Centrifugation", 0 ),
Add Factor( Discrete Numeric, {0, 2}, "Concentration cycles", 0 ),
Add Factor( Blocking, 4, "Block" ), Set Random Seed( 2118942861 ),
Number of Starts( 1 ), Add Term( {1, 0} ), Add Term( {1, 1} ),
Add Term( {2, 1} ), Add Term( {3, 1} ), Add Term( {4, 1} ), Add Term( {5, 1} ),
Add Term( {6, 1} ), Add Term( {7, 1} ), Add Alias Term( {1, 1}, {2, 1} ),
Add Alias Term( {1, 1}, {3, 1} ), Add Alias Term( {1, 1}, {4, 1} ),
Add Alias Term( {1, 1}, {5, 1} ), Add Alias Term( {1, 1}, {6, 1} ),
Add Alias Term( {2, 1}, {3, 1} ), Add Alias Term( {2, 1}, {4, 1} ),
Add Alias Term( {2, 1}, {5, 1} ), Add Alias Term( {2, 1}, {6, 1} ),
Add Alias Term( {3, 1}, {4, 1} ), Add Alias Term( {3, 1}, {5, 1} ),
Add Alias Term( {3, 1}, {6, 1} ), Add Alias Term( {4, 1}, {5, 1} ),
Add Alias Term( {4, 1}, {6, 1} ), Add Alias Term( {5, 1}, {6, 1} ),
Set Sample Size( 16 ), Optimality Criterion( "Make A-Optimal Design" ),
"A-Optimality Parameter Weights"n( [1 1 1 1 1 1 1 1 1 1] ),
Simulate Responses( 0 ), Save X Matrix( 0 ), Make Design}
)
希望這個回答對你有幫助
