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Between batch Bioequivalence based on between batch variability

Hi guys can any body suggest the path to perform the between batch bio equivalence based on mean difference between reference and test divided by between batch variability.

Advanced Statistical Modeling

Data Exploration and Visualization

Re: Between batch Bioequivalence based on between batch variability

You could apply the two one-sided t-tests after you specify the acceptable margin. H0: test < (reference - margin) or (reference + margin) < test. H1: (reference - margin) < test < (reference + margin). Both one-sided tests must be significant to claim equivalence.

JMP can perform this test for you in the Oneway platform if you have the data, not the summary statistics.

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