How to compare baseline data from Derivation and Validation Cohorts?I am assigned by my supervisor to independently perform an analysis for risk and score models for my study outcome. After cleaning my data and assigning two-third of my sample size as the Derivation cohort and the other as the validation cohort, the next step is to compare the baseline characteristics if they are statistically significant or not. At the moment these two sample sizes of cohorts are in two different data tables, having a similar number of column labels but different raw numbers, as the Derivation sample is larger. I have no knowledge on how to compare (Differences) for example the age between these two cohorts. Please could anyone assist me in how to perform the analysis on JMP?
AnalyticsData TableRe: How to compare baseline data from Derivation and Validation Cohorts?You need to read the document, Discovering JMP which is available from the Help pull down menu. There are also tutorials available under the Help menu. The Beginners Tutorial and the Two Means Tutorial should help you understand the direction to go.Re: How to compare baseline data from Derivation and Validation Cohorts?Thank you txnelson, I will go through Discovering JMP.Re: How to compare baseline data from Derivation and Validation Cohorts?Let's back up a minute. Can you share how you created these two, in your word, cohorts? Random selection/assignment? Or some other method? You could have set yourself up for real analytical trouble by picking just about any other method than a random selection/assignment.
And what do the words 'statistically significant' mean? Without a testable hypothesis they mean little. @txnelson 's advice is sound wrt to 'how to get JMP' to do various tests for significance of population/sample parameters.
Re: How to compare baseline data from Derivation and Validation Cohorts?I have a large population data set, this study has a follow-up period of 5 years, aiming at making prediction scores (Risk models), one of the best study designs is to randomly assign data set into Derivation Cohort (used to develop the score) and later use the Validation Cohort to assess the validity of the score. but before performing associations and predictive modeling analysis in the Derivation cohort, I have to compare the two data sets on the variables that I'm interested in. I am stuck at this point.
