I am working on a design with 2 continuous factors and one discrete numeric factor and I can't go above 12 runs for this design. When I look at the color map of correlations of this design, it shows correlation among the factors. I have tried different number of runs to see it gets better but it doesn't. If I go below 12 run, power of design decreses and I can't go more than 12 runs. Is there anything I can do about the orthogonality of the design? Also, does looking at estimation efficiency help in this case?