My understanding is that I can't sync what's on my (Mac) Desktop without putting it in the OneDrive folder (in which case it would stop showing up on the Desktop). How are you backing up large files?
How do you the big files into OneDrive, since the size limit is 15 GB? This is a bigger concern since I'd like to back up the Windows image I use for Parallels.
So, you're saving the VM backup to an external drive? My set-up is not vanilla (JMPC and SAS Metadata Server) and I'd rather not have to download and reinstall.