I assume that for multiple linear regression model in JMP, Lack of Fit's p value test (Prob > F) value signifies whether the whole model is significant or not right? Is it the case that if the value is less than 0.05 then we consider the model as statistically significant? What is the use of Analysis of Variance then or is there anything helpful for it's (Prob > F) value for the result findings? For a model, if we don't see if the value is not statistically significant (value is greater than 0.05) then should we assume the model can not explain the relationship at all between dependent and independent variables? Thanks in advance.